Aspirin exacerbated respiratory disease (AERD): molecular and cellular diagnostic & prognostic approaches

Aspirin exacerbated respiratory disease (AERD): molecular and cellular diagnostic & prognostic approaches

Aspirin-exacerbated respiratory disease (AERD) is characterised by immune cells dysfunction. This research aimed to research the molecular mechanisms concerned in AERD pathogenesis. Relevant literatures have been recognized by a PubMed search (2005-2019) of english language papers utilizing the phrases “Aspirin-exacerbated Read more

Diagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico

Diagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico

The progressive disseminated histoplasmosis (PDH) has been related with extreme illness and excessive danger of loss of life amongst individuals living with HIV (PLWHIV). Therefore, the objective of this multicenter, prospective, double-blinded study achieved in ten Mexican hospitals was to Read more

Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions

Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions

Fabry illness (FD) is a lysosomal storage dysfunction (LSD) characterised by the deficiency of α-galactosidase A (α-GalA) and the resultant accumulation of poisonous metabolites corresponding to globotriaosylceramide (Gb3) and globotriaosylsphingosine (lysoGb3). Early prognosis and acceptable well timed therapy of FD Read more

Molecular diagnostic assays for the detection of common bacterial meningitis pathogens: A narrative review

Molecular diagnostic assays for the detection of common bacterial meningitis pathogens: A narrative review

Bacterial meningitis is a significant world trigger of morbidity and mortality. Rapid identification of the aetiological agent of meningitis is crucial for scientific and public well being administration and illness prevention given the wide selection of pathogens that trigger the Read more

Immunohistochemistry and molecular genetics in the differential diagnostics of mesenchymal lesions of gastrointestinal tract

Immunohistochemistry and molecular genetics in the differential diagnostics of mesenchymal lesions of gastrointestinal tract

Although, in routine apply, the differential diagnostics of mesenchymal tumors of the gastrointestinal tract remains to be centered primarily on the appropriate prognosis of gastrointestinal stromal tumor and its additional therapeutic administration primarily based on predictive diagnostics, current progress in Read more

Disentangling Leucocytozoon parasite diversity in the neotropics: Descriptions of two new species and shortcomings of molecular diagnostics for leucocytozoids.

Disentangling Leucocytozoon parasite diversity in the neotropics: Descriptions of two new species and shortcomings of molecular diagnostics for leucocytozoids.

Avian communities from South America harbor a unprecedented diversity of Leucocytozoon species (Haemosporida, Leucocytozoidae). Here, of 890 birds sampled, 10 (1.2%) have been contaminated with Leucocytozoon parasites. Among them, two new species have been found and described. Leucocytozoon grallariae sp. nov. and Leucocytozoon neotropicalis sp. nov. have been Read more