Aspirin exacerbated respiratory disease (AERD): molecular and cellular diagnostic & prognostic approaches

Aspirin exacerbated respiratory disease (AERD): molecular and cellular diagnostic & prognostic approaches

Aspirin-exacerbated respiratory disease (AERD) is characterised by immune cells dysfunction. This research aimed to research the molecular mechanisms concerned in AERD pathogenesis. Relevant literatures have been recognized by a PubMed search (2005-2019) of english language papers utilizing the phrases “Aspirin-exacerbated Read more

Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions

Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions

Fabry illness (FD) is a lysosomal storage dysfunction (LSD) characterised by the deficiency of α-galactosidase A (α-GalA) and the resultant accumulation of poisonous metabolites corresponding to globotriaosylceramide (Gb3) and globotriaosylsphingosine (lysoGb3). Early prognosis and acceptable well timed therapy of FD Read more