Month: April 2021

Diagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico
Apr 23

Diagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico

The progressive disseminated histoplasmosis (PDH) has been related with extreme illness and excessive danger of loss of life amongst individuals living with HIV (PLWHIV). Therefore, the objective of this multicenter, prospective, double-blinded study achieved in ten Mexican hospitals was to Read more

Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions
Apr 07

Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions

Fabry illness (FD) is a lysosomal storage dysfunction (LSD) characterised by the deficiency of α-galactosidase A (α-GalA) and the resultant accumulation of poisonous metabolites corresponding to globotriaosylceramide (Gb3) and globotriaosylsphingosine (lysoGb3). Early prognosis and acceptable well timed therapy of FD Read more